Browsing by Author "Salzano, Francisco M."

Now showing 1 - 20 of 29
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    Anthropometric studies in Brazilian Cayapo indians
    (Wiley, 1972) Rocha, F. J. da; Salzano, Francisco M.
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    Apolipoprotein B genetic variability in Brazilian Indians
    (Wayne State University Press, 1999) Kaufman, Letícia; Vargas, André F.; Coimbra Junior, Carlos Everaldo Alvares; Santos, Ricardo Ventura; Salzano, Francisco M.; Hutz, Mara H.
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    Association of the low-density lipoprotein receptor gene with obesity in Native American populations
    (Springer, 2000) Mattevi, Vanessa S.; Coimbr Jr., Carlos E. A.; Santos, Ricardo Ventura; Salzano, Francisco M.; Hutz, Mara H.
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    Blood pressure levels in Xavánte adults from the Pimentel Barbosa Indian Reservation, Mato Grosso, Brazil
    (International Society on Hypertension in Blacks, 2001) Coimbra Junior, Carlos Everaldo Alvares; Chor, Dora; Santos, Ricardo Ventura; Salzano, Francisco M.
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    The Brazilian Xavante Indians revisited: new protein genetic studies
    (Wiley, 1997) Salzano, Francisco M.; Franco, M. H. L. P.; Weimer, T. A.; Callegari-Jacques, S. M.; Mestriner, M. A.; Hutz, M. H.; Flowers, Nancy M.; Santos, Ricardo Ventura; Coimbra Junior, Carlos Everaldo Alvares
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    Brief communication: 5-HTTLPR genetic diversity and mode of subsistence in Native Americans
    (American Journal of Physical Antrhopology, 2013) Bisso-Machado, Rafael; Ramallo, Virginia; Tarazona-Santos, Eduardo; Salzano, Francisco M.; Bortolini, Maria Cátira; Hünemeier, Tábita
    The relationship between the "individualism-collectivism" and the serotonin transporter functional polymorphism (5-HTTLPR), suggested in the previous reports, was tested in Native South Amerindian populations. A total of 170 individuals from 21 populations were genotyped for the 5-HTTLPR alleles. For comparative purposes, these populations were classified as individualistic (recent history of hunter-gathering) or collectivistic (agriculturalists). These two groups showed an almost identical S allele frequency (75 and 76%, respectively). The analysis of molecular variance showed no structural differences between them. Behavioral typologies like those suggested by JY Chiao and KD Blizinsky (Proc R Soc B 277 () 529-537) are always a simplification of complex phenomena and should be regarded with caution. In addition, classification of a whole nation in the individualist/collectivist dichotomy is controversial. The focus on modes of subsistence in preindustrial societies, as was tested here, may be a good alternative although the postulated association between the 5-HTTLPR S allele and the collectivist societies was not confirmed.
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    Brief Commuunication: Variability of innate immune system genes in Native American populations-relationship with history and epidemiology
    (American Association of Physical Anthropologists, 2016) Lindenau, Juliana Dal-Ri; Salzano, Francisco M.; Hurtado, Ana Magdalena; Hill, Kim R.; Petzl-Erler, Maria Luiza; Tsuneto, Luiza Tamie; Hutz, Mara Helena
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    The Caincang revisited: blood genetics and anthropometry.
    (Wiley, 1980) Salzano, Francisco M.; Callegari-Jacques, S. M.; Franco, M. H. L. P.; Hutz, M. H.; Weimer, T. A.; Silva, R. S.; Rocha, F. J.
    A total of 248 individuals belonging to four populations of Cain gang Indians from southern Brazil were studied in relation to 23 genetic systems that are expressed in blood and one manifested on saliva. These results were compared with those obtained in 400 members of these same communities that were subjected to 11 body measurements. Nine polymorphic loci (MNSs, P, Rh, Dully, Diego,Hp, PGM,, ESD, and Gc) were chosenfor the calculation of the genetic distances between the four populations, which were compared with Mahalanobis's D2 differences. The two sets of values proved to be intercorrelated but neither showed a relationship with the geographicdistances separatingthe four communi ties. The Caingang were previously classified linguistically as Ge, and they show several affinities with the Ge tribes, both when hematological, and morphological, characteristicsareconsidered. A variantPGDphenotype is alsodescribed, showing a curious storage effect
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    Contato agride saúde do índio.
    (Fundação Nacional do Índio (FUNAI), 1979) Salzano, Francisco M.
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    Cytokine genes are associated with tuberculin skin test response in a native Brazilian population
    (Elsevier, 2010) Zembrzuski, Verônica M.; Basta, Paulo Cesar; Callegari-Jacques, S. M.; Santos, Ricardo Ventura; Coimbra Junior, Carlos Everaldo Alvares; Salzano, Francisco M.; Hutz, Mara H.
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    D1S80 locus variability in three Brazilian ethnic groups
    (Wayne State University Press, 1995) Heidrich, Elisa M.; Hutz, Mara H.; Salzano, Francisco M.; Coimbra Junior, Carlos Everaldo Alvares; Santos, Ricardo Ventura
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    Estudos epidemiológicos entre populações indígenas da Amazônia. II. Prevalências da microfilaremia de Mansonella ozzardi: comparação de dois métodos de diagnóstico
    (El País (Brasil), 1980) Lawrence, Dale N.; Erdtmann, Bernardo; Peet, Jennifer W.; Mello, José A. Nunes de; Healy, George R.; Neel, James V.; Salzano, Francisco M.
    Foi determinada a prevalência de microfilaremia em uma amostra representativa de adolescentes e adultos, em 13 aldeias, de índios amazônicos brasileiros em julho-agosto de 1976. Através de esfregaço de sangue periférico corados com Giemsa e de preparações de culturas de linfócitos de sangue periférico, ou ambas, foram testadas 533 pessoas com idade acima de 10 anos e 68 crianças com menos de 10 anos. A Mansonella ozzardi foi a única espécie de microfilária encontrada. A prevalência foi altamente aldeia-específica. Em quatro (4) das 13 aldeias, houve casos de não detecção de microfilaremia pelos métodos usados. Em quatro (4) outras aldeias, as prevalências encontradas para os residentes de 10 anos e mais velhos foram em excesso de 60% para cada método utilizado. Em aldeias onde a microfilaremia foi documentada, apenas cinco (13%) do total de 38 crianças testadas foram positivas. Houve uma tendência geral da prevalência aumentar com o aumento da idade, A razão de prevalência de microfilaremia entre homens e mulheres foi de aproximadamente 1,4:1 para o teste de esfregaço de sangue periférico e exatamente 1:1 para o outro. Em cada 5 aldeões com microfilaremia-positiva testados com ambos os métodos, detectamos uma mais alta prevalência da microfilaremia com as preparações feitas de cultura de linfócitos.
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    Fibroblast growth factor receptor 1 (FGFR1) variants and craniofacial variation in Amerindians and related populations
    (American Journal of Human Biology, 2013) Gómez-Valdés, Jorge A.; Hünemeier, Tábita; Contini, Verônica; Acuña-Alonzo, Victor; Macin, Gastón; Ballesteros-Romero, Mónica; Corral, Pau; Ruiz-Linares, Andres; Sánchez-Mejorada, Gabriela; Canizales-Quinteros, Samuel; Martínez-Abadías, Neus; Salzano, Francisco M.; González-José, Rolando; Bortolini, Maria Cátira
    OBJECTIVES: The polymorphic site rs4647905 of the FGFR1 gene was previously associated with a decrease in cephalic index (CI). Here, we evaluate the relationships between genotypes and cephalometric measurements and indices in one Mexican Native and two mestizo Mexican populations using two haplotype-tag SNPs (rs4647905 and rs3213849) that represent >85% of the FGFR1 variability, plus three other SNPs (rs2293971, rs2304000, and rs930828) situated nearby. In addition, we genotyped five South American natives, two European, one African, and one Siberian populations to evaluate their intra and intercontinental population diversity. METHODS: The five SNPs were tested and the craniofacial measurements and indices were collected using standardized procedures. Principal Component Analysis was used to verify individual/population comparisons. Associations were performed through the generalized linear model (GLM), coefficient of determination R(2) and linear regression tests. RESULTS: We found a tendency for a decrease in CI in individuals homozygous for allele rs4647905C, regardless of the population to which they belong, though the effect is more pronounced in mestizo. When the GLM analyses were performed using the absolute/linear cephalometric measurements, a statistically significant association was found between four SNPs and head length in the mestizo population. CONCLUSIONS: FGFR1 polymorphisms, especially rs4647905, can have an important role in the normal human skull variation, primarily due to their influence in head length, which would affect other cephalometric absolute/linear measures as well as indices like CI as a result of the pervasive nature of the morphological integration that characterizes the human skull.
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    A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans
    (Oxford University Press, 2010) Acuña-Alonzo, Víctor; Flores-Dorantes, Teresa; Kruit, Janine K.; Villarreal-Molina, Teresa; Arellano-Campos, Olimpia; Hünemeier, Tábita; Moreno-Estrada, Andrés; Ortiz-López, Ma Guadalupe; Villamil-Ramírez, Hugo; León-Mimila, Paola; Villalobos-Comparan, Marisela; Jacobo-Albavera, Leonor; Ramírez-Jiménez, Salvador; Sikora, Martin; Zhang, Lin-Hua; Pape, Terry D.; Granados-Silvestre, Ma de Angeles; Montufar-Robles, Isela; Tito-Alvarez, Ana M.; Zurita-Salinas, Camilo; Bustos-Arriaga, José; Cedillo-Barrón, Leticia; Gómez-Trejo, Celta; Barquera-Lozano, Rodrigo; Vieira Filho, João Paulo B.; Granados, Julio; Romero-Hidalgo, Sandra; Huertas-Vázquez, Adriana; González-Martín, Antonio; Gorostiza, Amaya; Bonatto, Sandro L.; Rodríguez-Cruz, Maricela; Wang, Li; Tusié-Luna, Teresa; Aguilar-Salinas, Carlos A.; Lisker, Ruben; Moises, Regina S.; Menjivar, Marta; Salzano, Francisco M.; Knowler, William C.; Bortolini, M. Cátira; Hayden, Michael R.; Baier, Leslie J.; Canizales-Quinteros, Samuel
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    Further studies on the Xavante Indians. VI. The physical status of the Xavantes of Simões Lopes
    (Cell Press, 1967) Weinstein, E. David; Neel, James V.; Salzano, Francisco M.
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    Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes
    (PLOS, 2015) Jacovas, Vanessa Cristina; Rovaris, Diego Luiz; Peréz, Orlando; Azevedo, Soledad de; Macedo, Gabriel Souza; Sandoval, José Raul; Salazar-Granara, Alberto; Villena, Mercedes; Dugoujon, Jean-Michel; Bisso-Machado, Rafael; Petzl-Erler, Maria Luiza; Salzano, Francisco M.; Ashton-Prolla, Patricia; Ramallo, Virginia; Bortolini, Maria Cátira
    The diversity of the five single nucleotide polymorphisms located in genes of the TP53 pathway (TP53, rs1042522; MDM2, rs2279744; MDM4, rs1563828; USP7, rs1529916; and LIF, rs929271) were studied in a total of 282 individuals belonging to Quechua, Aymara, Chivay, Cabanaconde, Yanke, Taquile, Amantani, Anapia, Uros, Guarani Ñandeva, and Guarani Kaiowá populations, characterized as Native American or as having a high level (> 90%) of Native American ancestry. In addition, published data pertaining to 100 persons from five other Native American populations (Surui, Karitiana, Maya, Pima, and Piapoco) were analyzed. The populations were classified as living in high altitude (≥ 2,500 m) or in lowlands (< 2,500 m). Our analyses revealed that alleles USP7-G, LIF-T, and MDM2-T showed significant evidence that they were selected for in relation to harsh environmental variables related to high altitudes. Our results show for the first time that alleles of classical TP53 network genes have been evolutionary co-opted for the successful human colonization of the Andes.
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    Haplotype and allele frequencies for three genes of the dopaminergic system in South American Indians
    (Wiley-Liss, 2000) Hutz, Mara H.; Almeida, Silvana de; Coimbra Junior, Carlos Everaldo Alvares; Santos, Ricardo Ventura; Salzano, Francisco M.
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    High heterogeneity of apolipoprotein E gene frequencies in South American Indians
    (Taylor & Francis, 2000) Andrade, F. M. de; Coimbra Junior, Carlos Everaldo Alvares; Santos, Ricardo Ventura; Goicoechea, A.; Carnese, F. R.; Salzano, Francisco M.; Hutz, Mara H.
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    High prevalence of HBV/A1 subgenotype in native south Americans may be explained by recent economic developments in the Amazon
    (Elsevier, 2016) Godoy, Bibiane A.; Gomes-Gouvêa, Michele S.; Zagonel-Oliveira, Marcelo; Alvarado-Mora, Mónica V.; Salzano, Francisco M.; Pinho, João R. R.; Fagundes, Nelson J. R.
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    Human T-cell lymphotropic virus type II in Guaraní Indians, Southern Brazil
    (Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2005) Menna-Barreto, Márcio Menna; Bender, Ana Ligia; Bonatto, Sandro Luis; Freitas, Loreta B.; Salzano, Francisco M.; Tsuneto, Luiza T.; Petzl-Erlen, Maria Luiza