Uniparental genetic markers in South Amerindians

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dc.contributor.authorBisso-Machado, Rafael
dc.contributor.authorBortolini, Maria Cátira
dc.contributor.authorSalzano, Francisco M.
dc.creator.affilliationUniversidade Federal do Rio Grande do Sul. Departamento de Genética. Instituto de Biociências. Porto Alegre, RS, Brasilen_US
dc.date.accessioned2019-11-08T13:31:47Z
dc.date.available2019-11-08T13:31:47Z
dc.date.issued2012
dc.description.abstractenA comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 persons, and sequencing studies used either the complete mtDNA genome or the highly variable segments 1 and 2. The diversity of the markers made it difficult to establish a general picture of Y-chromosome variability in the populations studied. However, haplogroup Q1a3a* was almost always the most prevalent whereas Q1a3* occurred equally in all regions, which suggested its prevalence among the early colonizers. The STR allele frequencies were used to derive a possible ancient Native American Q-clade chromosome haplotype and five of six STR loci showed significant geographic variation. Geographic and linguistic factors moderately influenced the mtDNA distributions (6% and 7%, respectively) and mtDNA haplogroups A and D correlated positively and negatively, respectively, with latitude. The data analyzed here provide rich material for understanding the biological history of South Amerindians and can serve as a basis for comparative studies involving other types of data, such as cultural data.en_US
dc.identifier10.1590/S1415-47572012005000027
dc.identifier1678-4685
dc.identifier.citationBISSO-MACHADO, Rafael; BORTOLINI, Maria Cátira; SALZANO, Francisco M. Uniparental genetic markers in South Amerindians. Genetics and Molecular Biology, v. 35, n. 2, p. 365-387, 2012.en_US
dc.identifier.doi10.1590/S1415-47572012005000027
dc.identifier.issn1678-4685
dc.identifier.urihttps://repositorio.bvspovosindigenas.fiocruz.br/handle/bvs/1310
dc.language.isoeng
dc.publisherSociedade Brasileira de Genéticaen_US
dc.rightsopen accessen_US
dc.subject.decsSaúde de Populações Indígenasen_US
dc.subject.decsÍndios Sul-Americanosen_US
dc.subject.decsDNA Mitocondrialen_US
dc.subject.decsGenética Humanaen_US
dc.subject.enHealth of Indigenous Peoplesen_US
dc.subject.enIndians, South Americanen_US
dc.subject.enGenetics, Medicalen_US
dc.subject.otherÍndios Sul-Americanosen_US
dc.subject.otherSaúde de Populações Indígenasen_US
dc.subject.otherDNA Mitocondrialen_US
dc.subject.otherGenética Médicaen_US
dc.titleUniparental genetic markers in South Amerindiansen_US
dc.typeArticleen_US
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