Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil

dc.contributor.authorBlack, Francis L.
dc.contributor.authorSalzano, Francisco M.
dc.contributor.authorLayrisse, Zulay
dc.contributor.authorFranco, M. Helena L. P.
dc.contributor.authorHarris, Nancy S.
dc.contributor.authorWeimer, Tania A.
dc.creator.affilliationYale University School of Medicine. Department of Epidemiology and Public Health. New Haven, CT, USA.en_US
dc.creator.affilliationUniversidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.en_US
dc.creator.affilliationInstituto Venezolano de Investigaciones Científicas. Caracas, Venezuela.en_US
dc.creator.affilliationUniversidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.en_US
dc.creator.affilliationYale University School of Medicine. Department of Epidemiology and Public Health. New Haven, CT, USA.en_US
dc.creator.affilliationUniversidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.en_US
dc.date.accessioned2022-05-20T15:42:44Z
dc.date.available2022-05-20T15:42:44Z
dc.date.issued1980
dc.description.abstractenResults concerning HLA types and 22 other blood genetic systems are reported for the Parakanã Indians of northern Brazil, a tribe that is notable for the light color and pilosity of some of its members. No clear evidence of Caucasoid admixture was found, but the Parkanã show unusual frequencies in the EsD¹, PGM¹₁, Gc², Cpᴮ, Fyᵃ, Diᵃ, and Lᴹ genetic markers. In addition, the very rare Rh allele rʸ is present, as well as what seems to be a new PGM₂ variant. There is very limited heterogeneity in the HLA system. All these distinctive features may have arisen through a combination of founder effects and genetic drift. However, low Fᵢₛ values, as well as higher mean ages in heterozygous as compared to homozygous persons, suggest that an heterotic effect is counteracting these dispersive forces.en_US
dc.identifier.citationBLACK, Francis L. et al. Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil. American Journal of Physical Anthropology, v. 52, n. 1, p. 119-132, Jan. 1980.en_US
dc.identifier.doi10.1002/ajpa.1330520115
dc.identifier.eissn1096-8644
dc.identifier.issn0002-9483
dc.identifier.urihttps://repositorio.bvspovosindigenas.fiocruz.br/handle/bvs/6939
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsrestricted accessen_US
dc.subject.decsBrasilen_US
dc.subject.decsÍndios Sul-Americanosen_US
dc.subject.decsSaúde de Populações Indígenasen_US
dc.subject.decsAntígenos HLAen_US
dc.subject.decsEnzimasen_US
dc.subject.decsAntígenos de Grupos Sanguíneosen_US
dc.subject.decsProteínas Sanguíneasen_US
dc.subject.otherRegião Norteen_US
dc.subject.otherParakanãen_US
dc.subject.otherGrupo Sanguíneoen_US
dc.titleRestriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazilen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
908650301.pdf
Size:
2.12 MB
Format:
Adobe Portable Document Format
No Thumbnail Available
Name:
890432960.html
Size:
98.66 KB
Format:
Hypertext Markup Language
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Plain Text
Description: